Chemical Regulations

EPA is issuing significant new use rules (SNURs) under the Toxic Substances Control Act (TSCA) for certain chemical substances that were the subject of premanufacture notices (PMNs) and are also subject to an Order issued by EPA pursuant to TSCA. The SNURs require persons to notify EPA at least 90 days before commencing the manufacture (defined by statute to include import) or processing of any of these chemical substances for an activity that is designated as a significant new use in the SNUR. The required notification initiates EPA's evaluation of the conditions of that use for that chemical substance. In addition, the manufacture or processing for the significant new use may not commence until EPA has conducted a review of the required notification; made an appropriate determination regarding that notification; and taken such actions as required by that determination.

EPA is making a correction to a final rule that appeared in the Federal Register on August 26, 2026. The final rule established significant new use rules (SNURs) under the Toxic Substances Control Act (TSCA) for chemical substances that were the subject of premanufacture notices (PMNs) and Orders issued by EPA pursuant to TSCA. Subsequent to the publication, the Agency identified an error in a chemical name.

PMT (EUH450): Persistent, mobile and toxic substance. vPvM (EUH451): Very persistent and very mobile substance. EUH071: Corrosive to the ...

PMT (EUH450): Persistent, mobile and toxic substance. vPvM (EUH451): Very persistent and very mobile substance. EUH071: Corrosive to the respiratory ...

The Environmental Protection Agency (EPA or Agency) is proposing to extend certain compliance dates applicable to certain entities subject to the regulation of trichloroethylene (TCE) under the Toxic Substances Control Act (TSCA) until December 31, 2027, including for certain chemical processors in meeting the prohibition compliance deadline for the processing of TCE, industrial and commercial use of TCE as a processing aid, and associated wastewater disposal; and for refrigerant manufacturers in meeting the compliance deadline for phasing down TCE feedstock in the production of HFC-134a. This proposed compliance extension would allow for necessary and reasonable transition periods for regulated entities under TSCA section 6(d).

The European Chemicals Agency (ECHA) has received a new intention to identify 4,4'-methylenediphenol, also known as Bisphenol F (BPF) as a substance ...

Experts at the European Chemicals Agency have set out their reasons for recommending that 'forever chemical' trifluoroacetic acid (TFA) should be ...

Recently, TFA has been classified by the European Chemicals Agency (ECHA) as a substance that is “toxic to reproduction”, because it can harm the ...

ECHA recommends TFA's classification as a reprotoxic substance. Helsinki, 6 October 2026. The European Chemicals Agency's (ECHA) Committee for Risk ...

The Toxic Substances Control Act (TSCA) requires EPA to publish in the Federal Register a statement of its findings after its review of certain TSCA submissions when EPA makes a finding that a new chemical substance or significant new use is not likely to present an unreasonable risk of injury to health or the environment. Such statements apply to premanufacture notices (PMNs), microbial commercial activity notices (MCANs), and significant new use notices (SNUNs) submitted to EPA under TSCA. This document presents statements of findings made by EPA on such submissions during the period from June 1, 2026, to June 30, 2026.

... ECHA within six months of the substance's inclusion. For a company managing tens of thousands of part numbers across dozens of product lines, that ...

A substance that ECHA classifies as toxic to reproduction. That is why I wanted to bring 30 women to Brussels – new mothers, those who are ...

Experts at the European Chemicals Agency (ECHA) had recommended a derogation of just 10 years for military aircraft, and a 10-year review for use of ...

I look forward to working with them to help ECHA in implementing EU priorities for chemical safety, delivering on its strategic objectives and ...

The European Chemicals Agency is launching two specialized webinars in 2026 to help micro, small, and medium-sized enterprises navigate complex ...

In June, the risk assessment committee of the European Chemicals Agency (ECHA) adopted an opinion submitted by German regulators last year that ...

Then, ECHA periodically recommends a subset of those candidates for inclusion on Annex XIV, the formal Authorisation List. Once a substance lands on ...

The American Chemistry Council (ACC) along with the American Alliance for Innovation (AAI) – a coalition of more than 100 organizations -- provided a set of management principles to Doug Troutman, Assistant Administrator for the U.S. Environmental Protection Agency’s (EPA) Office of Chemical Safety and Pollution Prevention.  The coalition encouraged the EPA to consider the principles as a foundation as it develops future regulations under the Toxic Substances Control Act (TSCA).

The European Chemicals Agency (ECHA) will hold two webinars on September 23, 2026, and November 5, 2026, aimed at assisting micro, small, and...

ECHA's Risk Assessment Committee (RAC) adopted its opinion on the ... Oak Court Business, Centre Sandridge Park, Porters Wood, St Albans ...

The European Chemicals Agency (ECHA) has made the new hazard classes available in the International Uniform Chemical Information Database (IUCLID) for ...

The European Chemicals Agency, ECHA, has made clear that after the applicable transition period, it will be mandatory to indicate whether a substance ...

... substance changes. Importantly, ECHA states that where a substance does not meet the criteria for a new hazard class, the reasons for that ...

... toxic to bees and classified among PFAS substances. The objection ... ECHA considers classification as a carcinogenic substance unjustified.

The Risk Assessment Committee (RAC) of the European Chemicals Agency (ECHA), at its meeting on Tuesday 8 September, adopted an opinion on the new ...

In compliance with the Paperwork Reduction Act (PRA), this document announces the availability of and solicits public comment on the following Information Collection Request (ICR) that EPA is planning to submit to the Office of Management and Budget (OMB): Regulation of Persistent, Bioaccumulative, and Toxic Chemicals Under TSCA Section 6(h) identified by EPA ICR No. 2599.04 and OMB Control No. 2070-0213. This ICR represents a renewal of an existing ICR that is currently approved through April 31, 2027. In addition, this renewal consolidates the information collections covered under EPA ICR No. 2779.02 and OMB Control No. 2070-0230 with EPA ICR No. 2599.04. Before submitting the ICR to OMB for review and approval under the PRA, EPA is soliciting comments on specific aspects of the information collection that is summarized in this document. The ICR and accompanying material are available in the docket for public review and comment.

In compliance with the Paperwork Reduction Act (PRA), this document announces the availability of and solicits public comment on the following Information Collection Request (ICR) that EPA is planning to submit to the Office of Management and Budget (OMB): User Fees for the Administration of the Toxic Substances Control Act (TSCA) (EPA ICR No. 2569.07 and OMB Control No. 2070-0208). This ICR represents a renewal of an existing ICR that is currently approved through May 31, 2027. Before submitting the ICR to OMB for review and approval under the PRA, EPA is soliciting comments on specific aspects of the information collection that is summarized in this document. The ICR and accompanying material are available in the docket for public review and comment.

... toxic to the reproductive system. The institute's study found rats ... The European Commission subsequently asked ECHA to reopen its assessment to take ...

... chemical. ECHA RAC's latest determination was made after considering ... substance does not warrant a classification for carcinogenicity.

The Environmental Protection Agency (EPA or Agency) is announcing the availability of and seeking public comment on a draft risk evaluation under the Toxic Substances Control Act (TSCA) for 1,2- dichloropropane. The purpose of risk evaluations under TSCA is to determine whether a chemical substance presents an unreasonable risk of injury to health or the environment under the conditions of use (COUs), including unreasonable risk to potentially exposed or susceptible subpopulations identified as relevant to the risk evaluation by EPA, and without consideration of costs or non-risk factors. EPA is seeking comment on the draft risk evaluation for 1,2-dichloropropane.

This sixth edition provides an update on the use and implementation of non-animal testing methods and testing strategies used by companies to meet the information requirements. At the same time, it provides an overview of ECHA’s activities to promote the development and use of alternatives and discusses opportunities and challenges in moving away from animal testing for the risk assessment of chemicals in the current regulatory context.

The European Chemicals Agency (ECHA) organised an expert workshop in Helsinki on 17–18 February 2026 on the potential application of alternative methods—OECD Test Guidelines (TG) 236 (Fish Embryo Acute Toxicity Test) and 249 (RTgill W1 Cell Line Acute Toxicity Assay)—as replacements for the acute fish toxicity (AFT) test (OECD TG 203) for regulatory purposes. The workshop was part of the ECHA’s project “Filling in the gaps to support the application of alternative methods (OECD TG 236 and 249) to replace vertebrate acute fish toxicity testing”. ECHA’s project and the workshop were supported by a consortium of contractors, which were RPA Europe, INERIS, aQuatox Solutions and Ricardo. AFT data is a standard information requirement for hazard assessment of chemicals under several EU regulations. OECD TG 203 is currently widely used to generate acute fish toxicity data for regulatory purposes. While OECD TG 236 and TG 249 are increasingly used, uncertainties persist about their applicability domains, performance for difficult to test substances, and their capacity to provide hazard information comparable to TG 203. The workshop sought to discuss the key findings of ECHA’s project on the alternatives to acute fish toxicity testing, consolidate scientific understanding, identify gaps, and gather experts’ input to support regulatory use of these alternative methods as potential replacements to the TG 203. The workshop was split in two sessions, the first in the form of a plenary session with platform presentations and an open discussion, accessible also to online participants, and the second in the form of targeted discussions in breakout groups followed by a world café, reserved to onsite participants. In total, about 50 experts from different sectors (regulators, industry, contract research organisations, non-governmental organisation, academia) attended the workshop in person, whereas more than 100 experts followed the first session online.

On August 27, 2026, the European Chemicals Agency (ECHA) announced the addition of 10 new substance testing proposals and invited public comments ...

The Environmental Protection Agency (EPA or Agency) is announcing the availability of and seeking public comment on the draft risk evaluation under the Toxic Substances Control Act (TSCA) for trans-1,2-dichloroethylene. The purpose of risk evaluations under TSCA is to determine whether a chemical substance presents an unreasonable risk of injury to health or the environment under the conditions of use (COUs), including unreasonable risk to potentially exposed or susceptible subpopulations identified as relevant to the risk evaluation by EPA, and without consideration of costs or non-risk factors. EPA is seeking comment on the draft risk evaluation for trans- 1,2-dichloroethylene.

This document announces the Agency's receipt of new chemical submissions under the Toxic Substances Control Act (TSCA), including information about the receipt of a Premanufacture Notice (PMN), Significant New Use Notice (SNUN), Microbial Commercial Activity Notice (MCAN), and an amendment to a previously submitted notice; test information; a biotechnology exemption application; an application for a test marketing exemption (TME); and a notice of commencement of manufacture (defined by statute to include import) (NOC) for a new chemical substance. This document also provides a periodic status report on the new chemical substances that are currently under EPA review or have recently concluded review. EPA is hereby providing notice of receipt of this information, as required by TSCA, and an opportunity to comment. This document covers new chemical submissions that have passed an initial screening and, for PMNs, SNUNs and MCANs, were determined to be complete during the period from June 1, 2026, to June 30, 2026, regardless of the initial submission date.

The Environmental Protection Agency (EPA) has submitted an information collection request (ICR), Confidential Business Information Claims under the Toxic Substances Control Act (TSCA) (EPA ICR Number 2706.03, OMB Control Number 2070-0223) to the Office of Management and Budget (OMB) for review and approval in accordance with the Paperwork Reduction Act. This is a proposed extension of the ICR, which is currently approved through August 31, 2026. Public comments were previously requested via the Federal Register on April 27, 2026 during a 60-day comment period. This notice allows for an additional 30 days for public comments.

EPA is issuing significant new use rules (SNURs) under the Toxic Substances Control Act (TSCA) for certain chemical substances that were the subject of premanufacture notices (PMNs) and are also subject to an Order issued by EPA pursuant to TSCA. The SNURs require persons to notify EPA at least 90 days before commencing the manufacture (defined by statute to include import) or processing of any of these chemical substances for an activity that is designated as a significant new use in the SNUR. The required notification initiates EPA's evaluation of the conditions of that use for that chemical substance. In addition, the manufacture or processing for the significant new use may not commence until EPA has conducted a review of the required notification; made an appropriate determination regarding that notification; and taken such actions as required by that determination.

The Toxic Substances Control Act (TSCA) requires EPA to publish in the Federal Register a statement of its findings after its review of certain TSCA submissions when EPA makes a finding that a new chemical substance or significant new use is not likely to present an unreasonable risk of injury to health or the environment. Such statements apply to premanufacture notices (PMNs), microbial commercial activity notices (MCANs), and significant new use notices (SNUNs) submitted to EPA under TSCA. This document presents statements of findings made by EPA on such submissions during the period from May 1, 2026, to May 31, 2026.

The case, Swissinno Solutions v ECHA (T-417/26), concerns the active substance peanut butter, seeds of the groundnut (Arachis hypogaea L.) roasted ...

2018China TaiwanToxic and Concerned Chemical Substance Control Act ... ECHA screened substances based on the SoC criteria defined in Article ...

The Environmental Protection Agency (EPA or Agency) is announcing the availability of and seeking public comment on the draft risk evaluation under the Toxic Substances Control Act (TSCA) for ethylene dibromide. The purpose of risk evaluations under TSCA is to determine whether a chemical substance presents an unreasonable risk of injury to health or the environment under the conditions of use (COUs), including unreasonable risk to potentially exposed or susceptible subpopulations identified as relevant to the risk evaluation by EPA, and without consideration of costs or non-risk factors. EPA is seeking comment on the draft risk evaluation for ethylene dibromide.

Helsinki, 17 August 2026. The European Chemicals Agency (ECHA) is supporting the EU Commission in implementing the chemical safety aspects of the ...

In compliance with the Paperwork Reduction Act (PRA), this document announces the availability of and solicits public comment on the following Information Collection Request (ICR) that EPA is planning to submit to the Office of Management and Budget (OMB): Generic Clearance for TSCA Section 4 Test Rules, Test Orders, Enforceable Consent Agreements (ECAs), Voluntary Data Submissions, and Exemptions from Testing Requirement (Renewal) (EPA ICR No. 1139.52 and OMB Control No. 2070-0033). This ICR represents a renewal of an existing ICR that is currently approved through March 31, 2027. Before submitting the ICR to OMB for review and approval under the PRA, EPA is soliciting comments on specific aspects of the information collection that is summarized in this document. The ICR and accompanying material are available in the docket for public review and comment.

The Environmental Protection Agency (EPA or Agency) is announcing the availability of and seeking public comment on the draft risk evaluations under the Toxic Substances Control Act (TSCA) for o- dichlorobenzene (CASRN 95-50-1) and p-dichlorobenzene (CASRN 106-46-7). The purpose of risk evaluations under TSCA is to determine whether a chemical substance presents an unreasonable risk of injury to health or the environment under the conditions of use (COUs), including unreasonable risk to potentially exposed or susceptible subpopulations identified as relevant to the risk evaluation by EPA, and without consideration of costs or non-risk factors. EPA is seeking public comment on the draft risk evaluations for o-dichlorobenzene and p- dichlorobenzene.

ECHA compared the 6,000-substance list against packaging substance information provided by stakeholders and other sources (online and literature) ...

EPA is proposing significant new use rules (SNURs) under the Toxic Substances Control Act (TSCA) for certain chemical substances that were the subject of premanufacture notices (PMNs) and are also subject to an Order issued by EPA pursuant to TSCA. Once finalized, the SNURs would require persons who intend to manufacture (defined by statute to include import) or process any of these chemical substances for an activity that is proposed as a significant new use by this rulemaking to notify EPA at least 90 days before commencing that activity. The required notification initiates EPA's evaluation of the conditions of that use for that chemical substance. In addition, the manufacture or processing for the significant new use may not commence until EPA has conducted a review of the required notification, made an appropriate determination regarding that notification, and taken such actions as required by that determination.

The Environmental Protection Agency (EPA or Agency) is announcing the availability of and seeking public comment on the draft risk evaluation under the Toxic Substances Control Act (TSCA) for 1,1,2-trichloroethane. The purpose of risk evaluations under TSCA is to determine whether a chemical substance presents an unreasonable risk of injury to health or the environment under the conditions of use (COUs), including unreasonable risk to potentially exposed or susceptible subpopulations identified as relevant to the risk evaluation by EPA, and without consideration of costs or non-risk factors. EPA is seeking comment on the draft risk evaluation for 1,1,2-trichloroethane.

The U.S. Environmental Protection Agency (EPA or Agency) is finalizing an extension of certain compliance dates applicable to certain entities subject to the risk-management rules for perchloroethylene (PCE) and carbon tetrachloride (CTC) under the Toxic Substances Control Act (TSCA). EPA is extending certain Workplace Chemical Protection Program (WCPP) compliance dates for non-federal owners and operators to match the existing compliance dates for federal agencies and their contractors. For both PCE and CTC, this action extends the compliance date for initial monitoring for inhalation exposure to June 21, 2027, and extends the compliance date to meet the existing chemical exposure limit (ECEL), establish a regulated area, institute a workplace information and training program, provide any required respiratory personal protective equipment (PPE), and establish a respiratory PPE program to September 20, 2027. For PCE, EPA is also extending the compliance date for federal entities to institute a workplace information and training program to September 20, 2027, and for non-federal entities to establish and implement an exposure control plan to December 20, 2027.

This document announces the Agency's receipt of new chemical submissions under the Toxic Substances Control Act (TSCA), including information about the receipt of a Premanufacture Notice (PMN), Significant New Use Notice (SNUN), Microbial Commercial Activity Notice (MCAN), and an amendment to a previously submitted notice; test information; a biotechnology exemption application; an application for a test marketing exemption (TME); and a notice of commencement of manufacture (defined by statute to include import) (NOC) for a new chemical substance. This document covers new chemical submissions that have passed an initial screening and, for PMNs, SNUNs and MCANs, were determined to be complete, during the period from May 1, 2026, to May 31, 2026, regardless of the initial submission date.

The Toxic Substances Control Act (TSCA) requires EPA to publish in the Federal Register a statement of its findings after its review of certain TSCA submissions when EPA makes a finding that a new chemical substance or significant new use is not likely to present an unreasonable risk of injury to health or the environment. Such statements apply to premanufacture notices (PMNs), microbial commercial activity notices (MCANs), and significant new use notices (SNUNs) submitted to EPA under TSCA. This document presents statements of findings made by EPA on such submissions during the period from April 1, 2026, to April 30, 2026.

Commission amends ECHA Board of Appeal procedural rules to reflect new operating model and modernise digital procedures. This is a premium content.

EPA is issuing a significant new use rule (SNUR) under the Toxic Substances Control Act (TSCA) for a certain chemical substance that was the subject of a premanufacture notice (PMN) and is also subject to an Order issued by EPA pursuant to TSCA. The SNUR requires persons to notify EPA at least 90 days before commencing the manufacture (defined by statute to include import) or processing of this chemical substance for an activity that is designated as a significant new use in the SNUR. The required notification initiates EPA's evaluation of the conditions of that use for that chemical substance. In addition, the manufacture or processing for the significant new use may not commence until EPA has conducted a review of the required notification; made an appropriate determination regarding that notification; and taken such actions as required by that determination.

EFSA said that it and ECHA are continuing joint work on how PFAS pesticides break down into TFA and behave in soil and water, with results expected by ...

The updated rules make it clear that ECHA should support the development and use of non-animal methods when assessing chemical safety, helping ...

EPA is proposing significant new use rules (SNURs) under the Toxic Substances Control Act (TSCA) for certain chemical substances that were the subject of premanufacture notices (PMNs) and are also subject to an Order issued by EPA pursuant to TSCA. Once finalized, the SNURs would require persons who intend to manufacture (defined by statute to include import) or process any of these chemical substances for an activity that is proposed as a significant new use by this rulemaking to notify EPA at least 90 days before commencing that activity. The required notification initiates EPA's evaluation of the conditions of that use for that chemical substance. In addition, the manufacture or processing for the significant new use may not commence until EPA has conducted a review of the required notification, made an appropriate determination regarding that notification, and taken such actions as required by that determination.

The American Chemistry Council (ACC) and a coalition of 75 organizations representing a broad cross-section of the U.S. economy today sent a letter to the U.S. Environmental Protection Agency (EPA), the Occupational Safety and Health Administration (OSHA) and the Office of Management and Budget (OMB) to work with them to use Section 9 of the Toxic Substances Control Act (TSCA) to establish a single, consistent federal framework for worker chemical safety.

Council Decision appointing one member of the Management Board of the European Chemicals Agency (ECHA)

chemical, eu, european union, Council of the European Union, EP, European. Related Practices & Jurisdictions. Environmental Energy Resources.

Entry 78 of Annex XVII of the REACH Regulation, introduced by Commission Regulation (EU) 2023/2055 of 25 September 2023 (commonly known as “the microplastics restriction”), hereafter referred to as “the restriction”, sets out reporting requirements for certain uses of synthetic polymer microparticles (SPMs) subject to a derogation. The purpose of this document is to help manufacturers, industrial downstream users and suppliers of SPM comply with the annual reporting requirements to ECHA. The reporting is done in a IUCLID format, and the dossier is submitted to ECHA via REACH-IT. According to the restriction, the purpose of the reporting requirements is to contribute to the monitorability of the effectiveness of the instructions for use and disposal and improve the evidence base for the risk management of the uses exempted from the prohibition of placing on the market. To ensure the optimal use of the reported information and facilitate enforcement, the information is made available to the Member States by ECHA.

... (ECHA), which will allow the European Parliament and member ... even when we are up against the many lobbyists of the chemical lobby,” he added.

... ECHA has the expertise and financial resilience to carry a rapidly growing workload ... EU Today has reported how the supply of specialised chemical ...

A provisional deal would strengthen ECHA's legal base, funding flexibility and independence as Europe confronts wider chemical safety demands The ...

The EU provides ECHA with its own regulation, a single budget, and more scientific and financial tools to better manage chemical risks.

The European Chemicals Agency (ECHA) has released its latest report on the use of alternatives to animal testing under the REACH regulation.

This document announces the Agency's receipt of new chemical submissions under the Toxic Substances Control Act (TSCA), including information about the receipt of a Premanufacture Notice (PMN), Significant New Use Notice (SNUN), Microbial Commercial Activity Notice (MCAN), and an amendment to a previously submitted notice; test information; a biotechnology exemption application; an application for a test marketing exemption (TME); and a notice of commencement of manufacture (defined by statute to include import) (NOC) for a new chemical substance. This document also provides a periodic status report on the new chemical substances that are currently under EPA review or have recently concluded review. EPA is hereby providing notice of receipt of this information, as required by TSCA, and an opportunity to comment. This document covers new chemical submissions that have passed an initial screening and, for PMNs, SNUNs and MCANs, were determined to be complete during the period from 04/1/2026 to 04/ 30/2026 regardless of initial submission date.

The Environmental Protection Agency (EPA or Agency) is announcing two virtual public meetings of the Science Advisory Committee on Chemicals (SACC). The first is a preparatory meeting scheduled for July 23, 2026. During the meeting, the SACC will consider the scope and clarity of the draft charge questions for the peer review of the draft technical support documents for 1,2-dichloropropane (1,2- DCP), 1,1,2-trichloroethane (1,1,2-TCA), trans-1,2-dichloroethylene (tDCE), 4,4'-(1-Methylethylidene)bis[2, 6-dibromophenol] (TBBPA), and ethylene dibromide (EDB). The second is the virtual SACC peer review meeting which will be held August 3 through 7, 2026, for the SACC to consider the draft technical support documents for 1,2-DCP, 1,1,2-TCA, tDCE, TBBPA, and EDB, and public comments on those materials. EPA is also announcing the availability of and soliciting public comment on the draft documents and charge questions that will be provided to the SACC for this peer review. The draft technical support documents were prepared under the Toxic Substances Control Act (TSCA) and will be submitted to the SACC for peer review.

The European Chemicals Agency (ECHA)'s Risk Assessment Committee (RAC) has concluded that trifluoroacetic acid (TFA), formed in the atmosphere by ...

Dr. Sharon McGuinness, Executive Director of the European Chemicals Agency (ECHA) about ECHA's evolving roles, future strategies, achievements, ...

We have launched a LinkedIn newsletter to keep you up to date on the latest developments across the chemical industry including food and FCMs and ...

The Environmental Protection Agency (EPA or Agency) is announcing the availability of and seeking public comment on the draft risk evaluation under the Toxic Substances Control Act (TSCA) for 4,4'- (1-Methylethylidene)bis[2,6-dibromophenol] (TBBPA). The purpose of risk evaluations under TSCA are to determine whether a chemical substance presents an unreasonable risk of injury to human health or the environment under the conditions of use (COUs), including unreasonable risk to potentially exposed or susceptible subpopulations identified as relevant to the risk evaluation by EPA, and without consideration of costs or non-risk factors. EPA is seeking comment on the draft risk evaluation for TBBPA.

This document announces the Agency's receipt of new chemical submissions under the Toxic Substances Control Act (TSCA), including information about the receipt of a Premanufacture Notice (PMN), Significant New Use Notice (SNUN), Microbial Commercial Activity Notice (MCAN), and an amendment to a previously submitted notice; test information; a biotechnology exemption application; an application for a test marketing exemption (TME); and a notice of commencement of manufacture (defined by statute to include import) (NOC) for a new chemical substance. This document also provides a periodic status report on the new chemical substances that are currently under EPA review or have recently concluded review. EPA is hereby providing notice of receipt of this information, as required by TSCA, and an opportunity to comment. This document covers new chemical submissions that have passed an initial screening and, for PMNs, SNUNs and MCANs, were determined to be complete during the period from 03/1/2026 to 03/ 31/2026 regardless of initial submission date.

Following the publication of the European Commission's roadmap towards phasing out animal testing for chemical safety assessments on 1 June, ECHA ...

ECHA said trifluoroacetic acid (TFA), a substance used in pesticides and air-conditioning systems, may harm unborn children and negatively affect ...

The Key Areas of Regulatory Challenge (KARC) report was originally developed by the European Chemicals Agency (ECHA) to support activities under ...

It has been put forward for further regulatory control by the European Chemical Agency (ECHA) expert Risk Assessment Committee (RAC) under the EU's ...

Further information. ECHA. We have launched a LinkedIn newsletter to keep you up to date on the latest developments across the chemical industry ...

'Forever chemical' TFA toxic to reproduction, ECHA experts conclude. (link is external). Submitted by pane on June 11, 2026 - 11:20 ...

... (ECHA) proposed classifying trifluoroacetic acid (TFA) as a substance that can harm fertility and unborn children. The agency's risk-assessment ...

Days later, the European Chemicals Agency (ECHA) officially classified trifluoroacetic acid (TFA) — a substance often called a “forever chemical” — as ...

The European Chemicals Agency (ECHA) said Wednesday that it was recommending that the so-called forever chemical TFA should be designated as toxic ...

Environmentalists are pushing for a faster clamp-down on fluorinated pesticides in light of a decision to classify a widespread degradation product as ...

The agency says the goal is to reinforce the scientific foundation behind EU chemicals regulation while supporting safer innovation, ...

The European Chemicals Agency (ECHA) has officially classified trifluoroacetic acid (TFA) as toxic to reproduction (Category 1B), concluding it ...