ECHA adds three hazardous chemicals to the Candidate List · Impact of the UK-India FTA on Indian chemical industry · View More · Interviews ...
The European Commission has asked experts at the European Chemical Agency to revisit their assessment of the carcinogenicity of the pesticide ...
Chemicals Agency (ECHA) a dossier supporting the identification of melamine as a substance of very high concern, i.e. a chemical substance ...
ENVI News 03 & 07 July 2025: EU-UK Trade and Cooperation Agreement, battery due diligence, marine biodiversity, CBAM, chemicals, biological control agents, Roswall on water resilience strategy
ENVI News 24 June: COP30, climate adaptation, agriculture and sustainable development goals
ENVI News 03-04 June: Executive Director of ECHA, Preparedness Union Strategy, vote on Soil Monitoring and REGI opinion on mid-term review
ENVI News 12-13 May: Exchanges of views with Commissioners Lahbib, Varhelyi and Séjourné, agriculture, protected species and CBAM
ENVI News 23-24 April and 5 May: Climate COP30 preparations, implementation of EU water legislation, PFAS and structured dialogue with Commissioner Hoekstra
ENVI News 7-8 April 2025: Commissioner Roswall, EFSA Director, air quality, eco-design, water resilience, taxonomy and budget
ENVI News 17-18, 19, 20 March 2025: EVP Ribera, EEA Ex. Director, sustainable transport, CBAM, end-of-life vehicles, forests, objections on LIFE programme, SDGs.
ENVI News 17-18 February: Water resilience, end-of-life of vehicles, one-substance-one-assessment, forest monitoring
ENVI News 13, 16 & 23 Jan 2025: Forests, climate adaptation, GMOs&novel food, end of live vehicles, microplastics, Polish Minister Paulina Hennig-Kloska
ENVI News 27-28 January: Water resilience, food controls, climate, cats and dogs
ENVI News 4-5 December 2024: Presentation of EU Agencies' work, Climate reports, Budget Discharges 2023, WHO on Antimicrobial resistance, adoption of negotiation mandates
ENVI News 14 October 2024: Deforestation Regulation & objections to the authorisation of GMOs
ENVI News 04 November 2024: Confirmation Hearings from 4 to 12 November 2024
ENVI News 3 October: NGTs, Clean Transition Dialogues update, Plastic Treaty and CBD COP16
ENVI News 23 September: Exchanges of views with the Hungarian Presidency
Source : © European Union, 2025 - EP
The European Chemicals Agency (ECHA) has recently added two more substances to its list of chemicals that could potentially harm people or the ...
In compliance with the Paperwork Reduction Act (PRA), this document announces the availability of and solicits public comment on the following Information Collection Request (ICR) that EPA is planning to submit to the Office of Management and Budget (OMB): "Notification of Substantial Risk of Injury to Health and the Environment under TSCA Section 8(e)" (EPA ICR No. 0794.18 and OMB Control No. 2070-0046). This ICR represents a renewal of an existing ICR that is currently approved through April 30, 2026. Before submitting the ICR to OMB for review and approval under the PRA, EPA is soliciting comments on specific aspects of the information collection that is summarized in this document. The ICR and accompanying material are available in the docket for public review and comment.
The European Chemicals Agency (ECHA) has announced the addition of three new substances to its Candidate List of Substances of Very High Concern ...
Reviewing recent developments, Klinger noted that the European Chemicals Agency (ECHA) ... With fluoropolymers widely used in gaskets for their chemical ...
Importers and producers of articles have to notify ECHA if their article contains a Candidate List substance within six months from the date it has ...
Following a decision at the ECHA's member state committee on 16 June, the European Chemicals Agency (ECHA) announced on Wednesday the inclusion in the ...
... Court in Case T-366/22, Ryanair Vs. Commission (Condor II ; COVID ... ECHA adds three hazardous chemicals to the Candidate List - ECHA/NR/25/20 ...
The European Chemicals Agency (ECHA) has added three new hazardous chemicals to its 'Candidate List' of substances of very high concern (SVHCs), ...
... Chemicals Agency (ECHA) said in a statement. A third substance, used in textile treatment products and dyes, was described as toxic for reproduction.
In compliance with the Paperwork Reduction Act (PRA), this document announces the availability of and solicits public comment on the following Information Collection Request (ICR) that EPA is planning to submit to the Office of Management and Budget (OMB): Request for Contractor Access to TSCA Confidential Business Information (CBI) (EPA ICR No. 1250.13 and OMB Control No. 2070-0075). This ICR represents a renewal of an existing ICR that is currently approved through April 30, 2026. Before submitting the ICR to OMB for review and approval under the PRA, EPA is soliciting comments on specific aspects of the information collection that is summarized in this document. The ICR and accompanying material are available in the docket for public review and comment.
ECHA’s achievements in 2024 reflect a strong commitment to our strategic goals and priorities, as well as our vision of chemical safety through science, collaboration and knowledge. We continued to progress and implement our existing legal mandate and also commenced implementation of several new tasks. Our role continues to expand, and in 2024, we supported decision makers as they prepared for the introduction of further new regulatory tasks for the Agency. Throughout the year, we collaborated closely with our many stakeholders, including Member States, the Commission, EU agencies, industry and NGOs. This engagement ensures we can deliver transparent, independent and high-quality scientific opinions and decisions and ensure duty holders meet their legal obligations. While much has been achieved in 2024, the Agency continues to face challenges, which will need to be addressed over the coming period. However, we also took steps to address how the Agency can tackle several of these challenges by modifying our ways or working in the future.
Juliane Glüge researched PFASs at ETH Zurich until the end of May. Until recently, she represented the European Chemical Society in the ECHA committee ...
ENVI News 24 June: COP30, climate adaptation, agriculture and sustainable development goals
ENVI News 03-04 June: Executive Director of ECHA, Preparedness Union Strategy, vote on Soil Monitoring and REGI opinion on mid-term review
ENVI News 12-13 May: Exchanges of views with Commissioners Lahbib, Varhelyi and Séjourné, agriculture, protected species and CBAM
ENVI News 23-24 April and 5 May: Climate COP30 preparations, implementation of EU water legislation, PFAS and structured dialogue with Commissioner Hoekstra
ENVI News 7-8 April 2025: Commissioner Roswall, EFSA Director, air quality, eco-design, water resilience, taxonomy and budget
ENVI News 17-18, 19, 20 March 2025: EVP Ribera, EEA Ex. Director, sustainable transport, CBAM, end-of-life vehicles, forests, objections on LIFE programme, SDGs.
ENVI News 17-18 February: Water resilience, end-of-life of vehicles, one-substance-one-assessment, forest monitoring
ENVI News 13, 16 & 23 Jan 2025: Forests, climate adaptation, GMOs&novel food, end of live vehicles, microplastics, Polish Minister Paulina Hennig-Kloska
ENVI News 27-28 January: Water resilience, food controls, climate, cats and dogs
ENVI News 4-5 December 2024: Presentation of EU Agencies' work, Climate reports, Budget Discharges 2023, WHO on Antimicrobial resistance, adoption of negotiation mandates
ENVI News 14 October 2024: Deforestation Regulation & objections to the authorisation of GMOs
ENVI News 04 November 2024: Confirmation Hearings from 4 to 12 November 2024
ENVI News 3 October: NGTs, Clean Transition Dialogues update, Plastic Treaty and CBD COP16
ENVI News 23 September: Exchanges of views with the Hungarian Presidency
Source : © European Union, 2025 - EP
Comput Toxicol. 2024 Sep 1;31:100327. doi: 10.1016/j.comtox.2024.100327.
ABSTRACT
Per- and Polyfluoroalkyl substances (PFAS) are a class of manufactured chemicals that are in widespread use and many present concerns for persistence, bioaccumulation and toxicity. Whilst a handful of PFAS have been characterized for their hazard profiles, the vast majority have not been extensively studied. Herein, a chemical category approach was developed and applied to PFAS that could be readily characterized by a chemical structure. The PFAS definition as described in the Toxic Substances Control Act (TSCA) section 8(a)(7) rule was applied to the Distributed Structure-Searchable Toxicity (DSSTox) database to retrieve an initial list of 13,054 PFAS. Plausible degradation products from the 563 PFAS on the non-confidential TSCA Inventory were simulated using the Catalogic expert system, and the unique predicted PFAS degradants (2484) that conformed to the same PFAS definition were added to the list resulting in a set of 15,538 PFAS. Each PFAS was then assigned into a primary category using Organisation for Economic Co-operation and Development (OECD) structure-based classifications. The primary categories were subdivided into secondary categories based on a chain length threshold (>=7 vs < 7). Secondary categories were subcategorized using chemical fingerprints to achieve a balance between total number of structural categories vs. level of structural similarity within a category based on the Jaccard index. A set of 128 terminal structural categories were derived from which a subset of representative candidates could be proposed for potential data collection, considering the sparsity of relevant toxicity data within each category, presence on environmental monitoring lists, and the ability to identify plausible manufacturers/importers. Refinements to the approach taking into consideration ways in which the categories could be updated by mechanistic data and physicochemical property information are also described. This categorization approach may be used to form the basis of identifying candidates for data collection with related applications in QSAR development, read-across and hazard assessment.
PMID:40547594 | PMC:PMC12181936 | DOI:10.1016/j.comtox.2024.100327
The Toxic Substances Control Act (TSCA) requires EPA to publish in the Federal Register a statement of its findings after its review of certain TSCA submissions when EPA makes a finding that a new chemical substance or significant new use is not likely to present an unreasonable risk of injury to health or the environment. Such statements apply to premanufacture notices (PMNs), microbial commercial activity notices (MCANs), and significant new use notices (SNUNs) submitted to EPA under TSCA. This document presents statements of findings made by EPA on such submissions during the period from April 1, 2025 to April 30, 2025.
The Environmental Protection Agency (EPA or Agency) is extending the postponement of the effective date of certain regulatory provisions of the final rule entitled "Trichloroethylene (TCE); Regulation Under the Toxic Substances Control Act (TSCA)" for an additional 60 days. Specifically, this postponement applies to the conditions imposed on the uses with TSCA exemptions.
The Environmental Protection Agency (EPA or Agency) is announcing the availability of the final risk evaluation under the Toxic Substances Control Act (TSCA) for 1,1-dichloroethane (CASRN 75- 34-3). The purpose of risk evaluations under TSCA is to determine whether a chemical substance presents an unreasonable risk of injury to health or the environment under the conditions of use, including unreasonable risk to potentially exposed or susceptible subpopulations identified as relevant to the risk evaluation by EPA, and without consideration of costs or non-risk factors. EPA used the best available science to prepare this final risk evaluation and determined, based on the weight of scientific evidence, that 1,1-dichloroethane presents unreasonable risk to human health driven by three conditions of use because of risks to workers.
EPA is issuing significant new use rules (SNURs) under the Toxic Substances Control Act (TSCA) for certain chemical substances that were the subject of premanufacture notices (PMNs) and are also subject to an Order issued by EPA pursuant to TSCA. The SNURs require persons to notify EPA at least 90 days before commencing the manufacture (defined by statute to include import) or processing of any of these chemical substances for an activity that is designated as a significant new use in the SNUR. The required notification initiates EPA's evaluation of the conditions of that use for that chemical substance. In addition, the manufacture or processing for the significant new use may not commence until EPA has conducted a review of the required notification; made an appropriate determination regarding that notification; and taken such actions as required by that determination.
... chemical and certain forms of cancer. Yet, the European Union has extended its ... ECHA, the European authorities for food and chemical safety.
... ECHA" on "various topics related to chemicals." In the fall of 2024, it secured a new advisory contract lasting until 2030. Ramboll also advised ...
It would also empower the European Chemicals Agency (ECHA) to generate data when needed and ensure transparency of scientific studies. Under the ...
The German Federal Environment Agency (UBA) has applied to the European Chemicals Agency (ECHA) for TFA to be classified as toxic for reproduction.
... chemicals, and ensure early detection and action on emerging chemical risks. ... The press release notes that the OSOA package will help ECHA, and other ...
The agreed text includes provisions for situations where the European Chemicals Agency (ECHA) and the European Food Safety Authority (EFSA) reach ...
The European Commission will task its chemicals agency (ECHA) and food safety watchdog (EFSA) with reviewing a new study linking the weed killer ...
A directive on the re-attribution of technical tasks to the European Chemicals Agency (ECHA). The new measures will contribute to the Commission's ...
It also empowers the European Chemicals Agency (ECHA) to generate data when needed and ensures transparency of scientific studies. Main elements of ...
EPA is issuing significant new use rules (SNURs) under the Toxic Substances Control Act (TSCA) for certain chemical substances that were the subject of premanufacture notices (PMNs) and are also subject to an Order issued by EPA pursuant to TSCA. The SNURs require persons to notify EPA at least 90 days before commencing the manufacture (defined by statute to include import) or processing of any of these chemical substances for an activity that is designated as a significant new use in the SNUR. The required notification initiates EPA's evaluation of the conditions of that use for that chemical substance. In addition, the manufacture or processing for the significant new use may not commence until EPA has conducted a review of the required notification; made an appropriate determination regarding that notification; and taken such actions as required by that determination.
... chemicals, and ensure early detection and action on emerging chemical risks. ... ECHA should provide access to all chemicals data generated or submitted ...
New guidance by the European Chemicals Agency (ECHA) on the application of Classification, Labelling and Packaging of Chemicals (CLP) criteria. An ...
Current priorities include evaluating the PFAS restriction proposal submitted by five Member States, on which ECHA's committees are preparing sectoral opinions to inform the Commission's and Member States' decisions. The One Substance, One Assessment package, adopted in December 2023, currently in inter-institutional negotiations , aims to streamline chemical risk assessments and will increase ECHA's responsibilities. Finally, a future proposal on ECHA's basic regulation is expected, which will revise its governance and consolidate its financing model to better support its growing mandate.
Source : © European Union, 2025 - EP
The European Chemicals Agency (ECHA) has updated its report on Key Areas of Regulatory Challenge with new topics in line with the European Union's ...
New guidance by the European Chemicals Agency (ECHA) on the application of Classification, Labelling and Packaging of Chemicals (CLP) criteria; An ...
The Environmental Protection Agency (EPA or Agency) is announcing that there will be two virtual public meetings of the Science Advisory Committee on Chemicals (SACC). On July 21, 2025, a preparatory meeting for the SACC to consider the scope and clarity of the draft charge questions for the peer review; and on August 4 through 8, 2025, a peer review meeting for the SACC to consider the dibutyl phthalate (DBP), the dicyclohexyl phthalate (DCHP), and the di(2- ethylhexyl) phthalate (DEHP) draft risk evaluations, as well as the technical support documents for butyl benzyl phthalate (also known as benzyl butyl phthalate, BBP) and diisobutyl phthalate (DIBP), and public comments. The charge questions will address scientific and technical issues identified for peer review in all five phthalate risk evaluations scheduled to be finalized in 2025. EPA is also announcing the availability of and soliciting public comment on the draft documents and charge questions that will be provided to the SACC for this peer review. The draft risk evaluations and technical support documents were prepared under the Toxic Substances Control Act (TSCA) and will be submitted to the SACC for peer review.
In compliance with the Paperwork Reduction Act (PRA), this document announces the availability of and solicits public comment on the following Information Collection Request (ICR) that EPA is planning to submit to the Office of Management and Budget (OMB): "Access to TSCA Confidential Business Information under TSCA section 14(d)(4), (5), and (6)," identified by EPA ICR No. 2570.03 and OMB Control No. 2070-0209. This ICR represents a renewal of an existing ICR that is currently approved through March 31, 2026. Before submitting the ICR to OMB for review and approval under the PRA, EPA is soliciting comments on specific aspects of the information collection that is summarized in this document. The ICR and accompanying material are available in the docket for public review and comment.
The Environmental Protection Agency (EPA or Agency) is amending the deadline for reporting pursuant to the Toxic Substances Control Act (TSCA) Health and Safety Data Reporting rule, which requires manufacturers (including importers) of 16 specified chemical substances to submit lists and copies of certain unpublished health and safety studies to the EPA. Specifically, the EPA is amending the reporting deadline for all 16 chemical substances subject to the rule to May 22, 2026, through final action.
The Environmental Protection Agency (EPA or Agency) is announcing the availability of and seeking public comment on the draft risk evaluations under the Toxic Substances Control Act (TSCA) for Dibutyl Phthalate (DBP) (CASRN 84-74-2) and Diethylhexyl Phthalate (DEHP) (CARSN 117-81-7). The purpose of risk evaluations under TSCA is to determine whether a chemical substance presents an unreasonable risk of injury to health or the environment under the conditions of use, including unreasonable risk to potentially exposed or susceptible subpopulations identified as relevant to the risk evaluation by EPA, and without consideration of costs or non-risk factors. EPA used the best available science to prepare this draft risk evaluation and to preliminarily determine, based on the weight of scientific evidence, that DBP and DEHP present unreasonable risk to health and the environment driven primarily by certain conditions of use analyzed in the draft evaluations.
To support its implementation, the European Chemicals Agency (ECHA) will update existing guidelines including these substances. This will help ...
The proper assessment of the confidentiality of the information contained in the ARs and PARs is important to ensure the correct dissemination of information on active substances (AS) and biocidal products (BP) as required under Article 67 of the Regulation (EU) 528/2012 (“Biocidal Products Regulation” (BPR)). It is also relevant in the context of Regulation (EC) No 1049/2001 (“ATD Regulation”) and equivalent national provisions, since the dissemination of ARs and PARs will possibly limit the number of access to documents requests. Note that these guidelines are without prejudice to confidentiality claims related to Directive 2003/4/EC on public access to environmental information. Two documents on the confidentiality claims check were prepared by ECHA (CA-March14-Doc.7.2.1 and CA-March14-Doc.7.2.23) and presented at the 55th CA meeting. A revised proposal for the assessment of confidentiality claims was agreed in the 56th CA meeting. This document elaborates guidelines in more detail on the general principles for assessing confidentiality requests by the evaluating body and on their practical application in relation to dissemination of ARs and PARs. Dissemination directly from the IUCLID dossier was not considered in this revision. The Biocides Submission Manual (BSM) Process of confidentiality requests for biocide applications provides information on the content of confidentiality claims and aims to help applicant for preparing their IUCLID dossiers.
... toxic substance by replacing it with safer, readily available alternatives. ... In 2022, the European Chemicals Agency (ECHA) conducted a comprehensive ...
ENVI News 03-04 June: Executive Director of ECHA, Preparedness Union Strategy, vote on Soil Monitoring and REGI opinion on mid-term review
ENVI News 12-13 May: Exchanges of views with Commissioners Lahbib, Varhelyi and Séjourné, agriculture, protected species and CBAM
ENVI News 23-24 April and 5 May: Climate COP30 preparations, implementation of EU water legislation, PFAS and structured dialogue with Commissioner Hoekstra
ENVI News 7-8 April 2025: Commissioner Roswall, EFSA Director, air quality, eco-design, water resilience, taxonomy and budget
ENVI News 17-18, 19, 20 March 2025: EVP Ribera, EEA Ex. Director, sustainable transport, CBAM, end-of-life vehicles, forests, objections on LIFE programme, SDGs.
ENVI News 17-18 February: Water resilience, end-of-life of vehicles, one-substance-one-assessment, forest monitoring
ENVI News 13, 16 & 23 Jan 2025: Forests, climate adaptation, GMOs&novel food, end of live vehicles, microplastics, Polish Minister Paulina Hennig-Kloska
ENVI News 27-28 January: Water resilience, food controls, climate, cats and dogs
ENVI News 4-5 December 2024: Presentation of EU Agencies' work, Climate reports, Budget Discharges 2023, WHO on Antimicrobial resistance, adoption of negotiation mandates
ENVI News 14 October 2024: Deforestation Regulation & objections to the authorisation of GMOs
ENVI News 04 November 2024: Confirmation Hearings from 4 to 12 November 2024
ENVI News 3 October: NGTs, Clean Transition Dialogues update, Plastic Treaty and CBD COP16
ENVI News 23 September: Exchanges of views with the Hungarian Presidency
Source : © European Union, 2025 - EP
The Toxic Substances Control Act (TSCA) requires EPA to publish in the Federal Register a statement of its findings after its review of certain TSCA submissions when EPA makes a finding that a new chemical substance or significant new use is not likely to present an unreasonable risk of injury to health or the environment. Such statements apply to premanufacture notices (PMNs), microbial commercial activity notices (MCANs), and significant new use notices (SNUNs) submitted to EPA under TSCA. This document presents statements of findings made by EPA on such submissions during the period from March 1, 2025 to March 31, 2025.
... substance covered by" the reporting rule and instead allow "robust summaries, similar to the approach adopted by the European Chemicals Agency" (ECHA) ...
Additionally, the European Chemicals Agency (ECHA)'s Member State Committee (MSC) meetings, where SVHC identification is discussed, have sessions open ...
... Chemicals Agency (ECHA) listings and, in many cases, making unvalidated safety and efficacy claims. Current biocide regulations. Understanding the ...
The European Chemicals Agency (ECHA) announced on May 20, 2025, that the redesigned Classification and Labeling (C&L) Inventory is now available ...
The European Chemicals Agency (ECHA) launched a consultation yesterday on the dossier from Germany's chemicals regulator, which advises the substance ...
The Environmental Protection Agency (EPA or Agency) is proposing to extend the compliance date applicable to certain entities subject to the regulation of methylene chloride recently promulgated under the Toxic Substances Control Act (TSCA). Specifically, EPA is proposing to extend by 18 months the Workplace Chemical Protection Program (WCPP) and the associated recordkeeping compliance dates for laboratories that are not owned or operated by agencies or Federal contractors acting on behalf of the Federal government. Under this proposal, all laboratories, whether federal or not, would have the same compliance dates, which would be aligned with current compliance dates for Federal agencies and Federal contractors. EPA is proposing to extend the compliance dates for associated laboratory activities detailed in this proposal to avoid disruption of important functions such as the use of environmental monitoring methods needed for cleanup sites and wastewater treatment, as well as activities associated with university laboratories. The use of environmental monitoring methods, a common function of non-federal laboratories, is important to EPA's mission to ensure that the air is safe to breathe, water is safe for drinking or recreating, and disposal activities protect the environment.
... toxic, very persistent and very mobile was officially submitted to the European Chemicals Agency (ECHA). One of the main sources of TFA in the ...
The PFAS proposals submitted to the ECHA in 2023 by Germany, the Netherlands, Norway, Sweden and Denmark, call for a ban on all PFAS substances under ...
To date, nearly 23,000 unique chemicals have been registered with ECHA. Join Anthesis sustainable chemistry experts for a two-part webinar series on ...
European Chemicals Agency's updated C&L Inventory now in ECHA CHEM offers easier access to 350000 substances, harmonized data, and new CLP hazard ...
... Chemicals Agency (ECHA) approach environmental assessments. The IUCN's ... chemical compounds, such as individual heavy metals and pesticides and their ...
Chemical. ECHA integrates classification and ...
Deadline: 2025-06-03
Approximate launch date: 05/06/2025
Deadline to register interest: 03/06/2025
In 2023 EFSA launched a project to promote the use of New Approach Methods (NAMs) into the risk assessment of pesticide residues metabolites (NAMs4PestRes) through the use of the OECD QSAR toolbox, a free available in silico tool managed by ECHA, to enhance connectivity of IUCLID and MetaPath and to implement embedded in silico models. The result will be an automated and standardized workflow for the assessment of mutagenicity (bacterial gene mutation) of pesticide residue metabolites to be implemented in a...
EXCLI J. 2025 Mar 27;24:479-507. doi: 10.17179/excli2024-7822. eCollection 2025.
ABSTRACT
Ethylbenzene (EB) was placed on List 2 for Tier 1 endocrine screening in the U.S. EPA's two-tiered Endocrine Disruptor Screening Program (EDSP) and was scheduled for evaluation under TSCA. Results of toxicology studies on EB were used to evaluate estrogen, androgen, thyroid, and steroidogenic (EATS) endpoints by a Weight of Evidence (WoE) methodology, as required by U.S. EPA and OECD guidelines for evaluating a chemical's endocrine disruptive potential. The WoE method involved problem formulation, systematic literature search and selection, data quality evaluation, relevance weighting of endpoint data, and application of specific interpretive criteria. Data on EB were sufficient to assess its effects on endpoints that would be expected to respond to chemicals that operate via EATS modes of action (MoAs) in various screening assays (Tier 1) and toxicity tests (Tier 2) that evaluate reproduction, development, and sub-chronic and chronic toxicity. In those studies, EB produced a pattern of responses inconsistent with the responses that would be expected for hormones and chemicals known to operate via EATS MoAs. Endocrine-sensitive endpoints that respond to EB administration generally do so only at dose levels above its kinetic maximum dose, indicating a lack of relevance to potential effects at lower dose levels in either the test species or humans. This comprehensive WoE evaluation demonstrates that EB lacks the potential to exhibit endocrine disruptive properties and cannot be deemed an endocrine disruptor or potential endocrine disruptor. Because this WoE evaluation was based largely on Tier 2-level studies of the type considered by the U.S. EPA and OECD to be more definitive than results of Tier 1 EDSP screening results, no additional useful information would be obtained by subjecting EB to further endocrine screening. As such, further endocrine screening of EB would be unjustified from animal welfare perspectives. This analysis supports a regulatory decision to halt further testing of EB for endocrine disruption unless unique and compelling data to the contrary arise. See also the graphical abstract(Fig. 1).
PMID:40376433 | PMC:PMC12078780 | DOI:10.17179/excli2024-7822
This action announces the availability of the EPA's response to a petition received on February 11, 2025, from the Clean Air Council, Communities for a Better Environment, and Natural Resources Defense Council (petitioners). The petition requests that EPA establish a TSCA rule prohibiting the use of hydrogen fluoride (HF) in domestic oil refining to eliminate unreasonable risks to public health and the environment. After careful consideration, EPA has denied the TSCA petition for the reasons set forth in this notice.
“This will be followed by a HFO ban from 2028/29.” A PFAS review is already underway in Europe with the European Chemicals Agency (ECHA) and ...
The Environmental Protection Agency (EPA or Agency) is amending the data submission period for the Toxic Substances Control Act (TSCA) PFAS reporting rule by changing the start date for submissions and making corresponding changes to the end dates for the submission period, i.e., the data submission period begins on April 13, 2026, and ends on October 13, 2026, with an alternate end date for small manufacturers reporting exclusively as article importers of April 13, 2027. As promulgated in October 2023, the regulation requires manufacturers (including importers) of perfluoroalkyl and polyfluoroalkyl substances (PFAS) in any year between 2011-2022 to report certain data to EPA related to exposure and environmental and health effects. This change is necessary because EPA requires more time to prepare the reporting application to collect this data. The Agency is separately considering reopening certain aspects of the rule to public comment. The delayed reporting date ensures that EPA has adequate time to consider the public comments and propose and finalize any modifications to the rule before the submission period begins.
The European Commission (EC) requested that the European Chemicals Agency (ECHA) assess the risks posed by certain hexavalent chromium substances.
... Chemicals Agency (ECHA). - 11th Euratom Conference on reactor safety ... Chemical Industries in Sweden (IKEM). - Oceans commissioner Costas ...
The European Commission (EC) requested that the European Chemicals Agency (ECHA) assess the risks posed by certain hexavalent chromium substances…
... Chemicals Authority (ECHA, Helsinki; www.echa.europa.eu) or the US Environmental Protection Agency (EPA, Washington, DC; www.epa.gov). Phthalates ...
In compliance with the Paperwork Reduction Act (PRA), this document announces the availability of and solicits public comment on the following Information Collection Request (ICR) that EPA is planning to submit to the Office of Management and Budget (OMB): "Consolidation of Certain Reporting and Recordkeeping Under Section 8 of the Toxic Substances Control Act (TSCA) (EPA ICR No. 2703.02 and OMB Control No. 2070-0224)." This ICR represents a renewal of an existing ICR that is currently approved through November 30, 2025. Before submitting the ICR to OMB for review and approval under the PRA, EPA is soliciting comments on specific aspects of the information collection that is summarized in this document. The ICR and accompanying material are available in the docket for public review and comment. EPA is also consolidating two ICRs covering reporting and recordkeeping activities under TSCA Section 8(a) to streamline the presentation of the paperwork burden estimates for these various activities and eliminate any duplication.
In compliance with the Paperwork Reduction Act (PRA), this document announces the availability of and solicits public comment on the following Information Collection Request (ICR) that EPA is planning to submit to the Office of Management and Budget (OMB) "TSCA Section 5 Premanufacture Review of New Chemical Substances and Significant New Use Rules for New and Existing Chemical Substances (EPA ICR No. 1188.16 and OMB Control No. 2070-0038)." This ICR represents a renewal of an existing ICR that is currently approved through December 31, 2025. Before submitting the ICR to OMB for review and approval under the PRA, EPA is soliciting comments on specific aspects of the information collection that is summarized in this document. The ICR and accompanying material are available in the docket for public review and comment.
The initial document “Recommendation of the BPC Working Groups: In situ generated active substances – Risk assessment and implications on data requirements for active substances generated in situ and their precursors” was agreed by the four BPC working groups (APCP, Efficacy, TOX and ENV WGs) in 2016 and 2017 and published on the ECHA website in 2017. At their meeting in July 2019, the Biocidal Competent Authorities agreed on the necessity to further develop recommendations also for the biocidal products of in situ generated active substances - isASs (Member State's Competent Authorities for biocidal products, 2019). Therefore, based on the collected experience with the granted approvals of isAS and the assessment of their precursors, the recommendations have been updated (version 2) and a new part on the biocidal products has been included. Current document “Recommendation of the BPC Working Groups (version 2): In situ generated active substances and their products - Information requirements and risk assessment for approval and authorisation.” was discussed in all four BPC working groups and agreed in March 2025. Principles applied to “conventional” active substances and biocidal products apply also to the isAS and their products, unless specified otherwise in this document. These recommendations are focusing on additional information needed and on the particularities in the assessment of isAS, their precursor(s) and BPs. These recommendations are intended for BPR applicants for active substance approval and authorisation of biocidal products and for evaluating Member State Competent Authorities (eCAs).
The Management Board welcomes the Annual Report 2024, fulfilling the requirements of the REACH Regulation (General Report)1 and those of the ECHA Financial Regulation (Consolidated Annual Activity Report)2. We consider that this report provides a comprehensive account of the activities carried out by ECHA during 2024, the performance of the Agency against the expected inputs, outputs and outcomes defined in the Single Programming Document 2024-20263. It also represents a fair overview of the evolution of ECHA’s budget, staffing, management, and its internal management system strategy and framework. This assessment is based on our analysis of all parts of the report, including the activities carried out, achievements, financial information, results of audits, retrospective evaluations, and the assessment of the internal control system, as well as the risks related to ECHA’s activities together with the corresponding mitigating measures.
This document announces the Agency's receipt of new chemical submissions under the Toxic Substances Control Act (TSCA), including information about the receipt of a Premanufacture notice (PMN), Significant New Use Notice (SNUN), Microbial Commercial Activity Notice (MCAN), and an amendment to a previously submitted notice; test information; a biotechnology exemption application; an application for a test marketing exemption (TME); and a notice of commencement of manufacture (defined by statute to include import) (NOC) for a new chemical substance. This document also provides a periodic status report on the new chemical substances that are currently under EPA review or have recently concluded review. EPA is hereby providing notice of receipt of this information, as required by TSCA, and an opportunity to comment. This document covers the period from 2/ 1/2025 to 2/25/2025.
It is the strictest law to date regulating chemical substances ... substances with a new European Chemicals Agency (ECHA) in Helsinki, Finland.
Following a request from the European Commission, the European Chemicals Agency (ECHA) has assessed the risks posed by certain hexavalent chromium ...
The Toxic Substances Control Act (TSCA) requires EPA to publish in the Federal Register a statement of its findings after its review of certain TSCA submissions when EPA makes a finding that a new chemical substance or significant new use is not likely to present an unreasonable risk of injury to health or the environment. Such statements apply to premanufacture notices (PMNs), microbial commercial activity notices (MCANs), and significant new use notices (SNUNs) submitted to EPA under TSCA. This document presents statements of findings made by EPA on such submissions during the period from February 1 to February 28, 2025.
Toxics. 2025 Mar 28;13(4):251. doi: 10.3390/toxics13040251.
ABSTRACT
Per- and polyfluoroalkyl substances (PFASs), while possessing desirable properties for human society, have increasingly raised concerns due to their environmental persistence, bioaccumulation, and ecotoxicity. One of the major challenges with PFASs is the inconsistent adoption of regulatory strategies by authorities across different countries and regions, making it difficult to address the issue on a global scale. To obtain a global overview of PFAS regulatory patterns, this study utilized the most recent PFAS regulatory databases across different jurisdictions, both local and global. Among all geographic regions, the United States Environmental Protection Agency (USEPA) and European Union (EU) Registration, Evaluation, Authorization, and Restriction of Chemicals (REACH) encompass the most jurisdictions for PFASs. However, most PFASs are without regulation under the current regulatory status. We also assessed the regulatory ecotoxicity status of PFASs under the Toxic Substances Control Act (TSCA) of the USEPA. The results showed that 36.3% of PFASs are of Unknown or Variable composition, Complex reaction products, or Biological materials (UVCB) and classified as E;P (persistent, bioaccumulative, and toxic), followed by 31.3% as P (persistent) and 13.2% as P;S (persistent and toxic). We highlight the regulatory patterns, industrial applications, and categorization of PFASs under different regulatory frameworks. The need for international cooperation and harmonized regulatory standards to mitigate PFAS pollution is also addressed. A coordinated effort involving regulatory agencies, industry, researchers, and the public will be essential to facilitate harmonized regulations of PFASs and ensure a sustainable and healthy environment.
PMID:40278567 | PMC:PMC12030800 | DOI:10.3390/toxics13040251
... substances every decade, adding extra costs and paperwork to their business operations. Additionally, the European Chemicals Agency (ECHA) will ...
ECHA - European Chemicals Agency; please note that the citation dates used for studies sourced from the ECHA website are the dates the dossiers ...
... chemical tech. The 3-year project is funded under the PREPARE ... Chemicals Agency (ECHA). This also affects the use of fluoroelastomers ...
Americans placed a great deal of importance on product affordability, U.S. jobs and manufacturing in addition to impact on the environment and human health when EPA is conducting reviews of new, innovative chemistries.
... chemical use in the European Union (EU). The ECHA (European Chemical Agency) website provides the latest updates on EDs, with the most recent list ...
... Chemicals Agency (ECHA). This also affects the use of fluoroelastomers ... chemical process technology and electrical applications. In the ...
A EU Chemicals Agency (ECHA) review of the categorization of ethanol used in disinfectants may lead to it being deemed a carcinogenic and reproductive ...
ECHA – Chromium (VI) restriction preparation: what you need to know. Chemicals, Webinars · ECHA – New ECHA chemical data availability system – Part II.
... Chemicals Agency (ECHA) and banned in the EU since 2009. Despite this, Dormex is just one on a long list of highly hazardous chemicals which ...
EPA is proposing significant new use rules (SNURs) under the Toxic Substances Control Act (TSCA) for certain chemical substances that were the subject of premanufacture notices (PMNs) and are also subject to an Order issued by EPA pursuant to TSCA. The SNURs require persons who intend to manufacture (defined by statute to include import) or process any of these chemical substances for an activity that is proposed as a significant new use by this rulemaking to notify EPA at least 90 days before commencing that activity. The required notification initiates EPA's evaluation of the conditions of that use for that chemical substance. In addition, the manufacture or processing for the significant new use may not commence until EPA has conducted a review of the required notification, made an appropriate determination regarding that notification, and taken such actions as required by that determination.
The Toxic Substances Control Act (TSCA) requires EPA to publish in the Federal Register a statement of its findings after its review of certain TSCA submissions when EPA makes a finding that a new chemical substance or significant new use is not likely to present an unreasonable risk of injury to health or the environment. Such statements apply to premanufacture notices (PMNs), microbial commercial activity notices (MCANs), and significant new use notices (SNUNs) submitted to EPA under TSCA. This document presents statements of findings made by EPA on such submissions during the period from January 1, 2025 to January 31, 2025. This document also presents statements of findings on submissions made by EPA during earlier time periods that were inadvertently omitted from notices for those time periods that were identified during a quality control review.
... Chemicals Agency (ECHA) submitted in 2022. Clay targets are typically manufactured using binders such as petroleum resin or pitch, or coal tar ...
Reclassifying ethanol as a carcinogenic, mutagenic, or reprotoxic substance - something the European Chemicals Agency seems likely to do in the ...
They include new requirements for the European Chemicals Agency (ECHA) to establish databases within the common data platform containing information ...
The Environmental Protection Agency (EPA or Agency) is postponing the effectiveness of certain regulatory provisions of the final rule entitled "Trichloroethylene (TCE); Regulation Under the Toxic Substances Control Act (TSCA)" for 90 days pending judicial review. Specifically, this postponement applies to the conditions imposed on the uses with TSCA exemptions.
ECHA – Chromium (VI) restriction preparation: what you need to know · Chemicals, Webinars · ECHA – New ECHA chemical data availability system – Part ...
Rīga meeting brings together EMA, EEA, EU-OSHA, ECDC, ENISA, CEPOL, BEREC, ECHA ... chemical products, transportation, IT and cybersecurity solutions ...
... Chemicals Agency (ECHA), which recognised resorcinol as an endocrine disruptor. However, the ECHA did not classify it as a “substance of very ...
Registration of chemical substances. Evaluation of the substances by the European Chemicals Agency (ECHA). Authorization for substances that are ...
The European Chemicals Agency (ECHA) has announced new testing of dozens of substances, including some used in cosmetics, personal care and fragrance.